Diazepam is N-demethylated by CYP3A4 and 2C19 for the Energetic metabolite N-desmethyldiazepam, and is particularly hydroxylated by CYP3A4 towards the Energetic metabolite temazepam. N-desmethyldiazepam and temazepam are both even further metabolized to oxazepam. Temazepam and oxazepam are mainly eliminated by glucuronidation.In acute Alcoholic bev